Immunophenotyping hPARR for Diagnosis of Canine Lymphomas
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چکیده
Immunophenotyping is essential for lymphocytecloned classification, prognosis and treatment option in human and canine lymphomas. Immunohistochemistry (IHC) is a classic method that is referred to a gold standard due to its accuracy (Valli et al., 2011; Thalheim et al., 2013). Regarding tissue specimens, it provides morphology of lymph nodes (LN) for histological assessment, but generalized anesthesia in dogs is required. Another immunophenotyping technique is immunocytochemistry (ICC). When compared to IHC, ICC is cheaper and easier. Fine needle aspiration biopsy (FNAB) can diagnose lymphoma by cytological classification; however, cell disruption, low cellularity or smear technique can lead to difficulty in interpretation (Aulbach et al., 2010; Sapierzynski, 2010). Nevertheless,
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تاریخ انتشار 2016